Updated August 9, 2026 · Reviewed by Dr. Pen Glow Editorial Team
This comparison answers one specific question: what is different between the Dr. Pen M8 and M8S, especially their cartridge systems? The similar names are misleading—their replacement cartridges are not interchangeable.
Direct Answer
The Dr. Pen M8 uses the M8/M7S cartridge family. The Dr. Pen M8S uses the separate M8S/A8S/A9/A11 family. Choose M8 if you already own M8/M7S cartridges or prefer its 11-pin and 16-pin options. Choose M8S if you already use the shared A8S/A9/A11 family or want its 12-pin and 18-pin options.
M8 vs M8S at a Glance
| Feature | M8 | M8S |
|---|---|---|
| Price checked Aug. 9, 2026 | $84.89 | $89.80 |
| Cartridge family | M8 / M7S | M8S / A8S / A9 / A11 |
| Current cartridge options | 11, 16, 24, 36, 42-pin; Nano-R/S | 12, 18, 24, 36, 42-pin; Nano-R/S |
| Speed levels | 6 on current main listing | 6 on current main listing |
| Charging | USB-C | USB-C |
| Operation | Current main listing describes wireless/corded use | Wireless/wired operation |
Live product pages are the final source for current prices, bundles and specifications.
The Deciding Difference: Cartridge Ecosystem
Do not order cartridges based on “M8” in the name alone. The M8/M7S replacement page explicitly says those cartridges are compatible only with M8 and M7S. The M8S/A8S/A9/A11 replacement page explicitly excludes M8.
If you are upgrading from another model, first use the Dr. Pen Cartridge Compatibility Guide. Existing cartridge inventory can matter more than the small price gap between these pens.
What the Two Models Share
Current product listings describe USB-C charging, multiple adjustable speeds, replaceable single-use cartridges and adjustable device controls. USB-C should therefore not be presented as an M8S-only advantage.
Why Choose M8?
- You already own M8/M7S cartridges.
- You specifically want the M8 family’s 11-pin or 16-pin options.
- You prefer its current lower device price.
Why Choose M8S?
- You already own M8S/A8S/A9/A11 cartridges.
- You specifically want 12-pin or 18-pin options.
- You value the current listing’s 3-lock bayonet, anti-backflow and low-vibration positioning.
For a broader four-model comparison, see M7 vs M7S vs M8 vs M8S. For premium shared-cartridge options, compare A11 vs M8S.
Safety and Scope
This page compares devices and compatibility; it does not prescribe needle depth, frequency, numbing products or treatment of medical conditions. The FDA states that no microneedling medical devices are authorized for over-the-counter sale. For medical microneedling or treatment suitability, consult a trained health-care professional.
Frequently Asked Questions
Can M8 and M8S use the same cartridges?
No. Their connector families are different.
Does M8 use USB-C?
Yes. The current M8 main product listing describes USB-C charging.
Which M8 cartridges are currently listed?
11-pin, 16-pin, 24-pin, 36-pin, 42-pin, Nano-R and Nano-S.
Which M8S cartridges are currently listed?
12-pin, 18-pin, 24-pin, 36-pin, 42-pin, Nano-R and Nano-S.
Is M8S automatically an upgrade for an M8 owner?
No. Moving to M8S also means moving to a different cartridge family.
Sources & References
- M8 product page
- M8S product page
- M8/M7S cartridges
- M8S/A8S/A9/A11 cartridges
- U.S. FDA: Microneedling Devices
- American Academy of Dermatology: Microneedling
Related Guides
- M7 vs M7S vs M8 vs M8S
- A11 vs M8S
- M9 vs M8S vs A11
- Cartridge Compatibility Guide
- Buyer’s Guide 2026
- Authenticity Guide
Editorial disclosure: Dr. Pen Glow sells both products. The comparison is based on current listings, compatibility and ownership considerations, not medical outcomes.
Last reviewed: August 9, 2026. Price, compatibility and key specifications are scheduled for monthly review.
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